Sometime ago I wrote an article on what it means to worship God in Spirit and Truth, I thought I will just emphasize a few things from that article.
True worship is impossible without Jesus Christ
In the conversation with the woman by the well Jesus says: "But the hour is coming, and is now here, when the true worshipers will worship the Father in spirit and truth, for the Father is seeking such people to worship him. (John 4:23)". Jesus is the one who makes that possible. He says "I am the way, and the truth, and the life. No one comes to the Father except through me. (John 14:6)". True worship is not centered around some special place, building or even a particular religious experience but around Jesus Christ.
True worship is impossible without the Holy Spirit
"God is spirit, and those who worship him must worship in spirit and truth.(John 4:24)". It is the Holy Spirit who convicts us of our sin and point us to Jesus Christ. It is also the Holy Spirit who empowers us to live a life worthy of the gospel. A life where we worship God in everything that we do.
"Worship of the living and true God is essentially an engagement with him on the terms that he proposes and in the way that he alone makes possible" - David Peterson